hrp0086p1-p723 | Pituitary and Neuroendocrinology P1 | ESPE2016

Effect of Dietary Control on Pubertal Onset and Immunoreactivity of Kisspeptin and Neurokinin B in Female Offspring Rats Fed High Fat Diet During Perinatal Period

Kim Eun Young , Jun Yonghyun , Yi Kyung Hee

Background: Nutrition is an important factor to regulate reproductive function. Some studies showed that high fat diet (HFD) may influence to puberty onset and irregular estrous cycles in the female rats. However, underlying regulation mechanism of nutrition on pubertal maturation and reproductive function is not well-known. Kisspeptin and neurokinin B (NKB) are an essential factor for regulation of pubertal development.Objective and hypotheses: In this ...